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What is recombinant vaccine?...

What is recombinant vaccine?

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A recombinant vaccine is produced by applying recombinant DNA technology. It involves the insertion of DNA encoding antigen (like bacterial surface protein) that can stimulate immune response in host cell and expresses the antigen. This antigen is then isolated, purified and cloned to high number and later processed.
Recombinant vaccines can be
Subunit recombinant vaccine, i.e., components of pathogenic organisms.
Attenuated recombinant vaccines, i.e., the genetically modified but weakened pathogenic agents.
Vector recombinant vaccines, i.e., genetically modified viral vectors.
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