During mitotic anaphase, chromatids migrate-

Options

A. From the metaphase plate towards the poles
B. Towards the nuclear envelope
C. Along with their sister chromatids toward one pole
D. None of these

Answer

**Step-by-Step Text Solution:**

1. **Understanding Mitosis**: Mitosis is the process of cell division that results in two genetically identical daughter cells. It consists of several phases: prophase, metaphase, anaphase, and telophase.

2. **Identifying Anaphase**: Anaphase is the stage of mitosis where the sister chromatids are separated and pulled apart. This occurs after the chromosomes have aligned at the metaphase plate during metaphase.

3. **Chromatid Separation**: During anaphase, the centromeres that hold the sister chromatids together divide. Each sister chromatid is then considered an individual chromosome.

4. **Direction of Movement**: The separated chromatids (now individual chromosomes) move towards opposite poles of the cell. This movement is facilitated by the spindle fibers that are attached to the centromeres.

5. **Reference Point - Metaphase Plate**: The metaphase plate is an imaginary line where the chromosomes were aligned during metaphase. As the chromatids move away from this plate, they travel towards the poles of the cell.

6. **Conclusion**: Therefore, during mitotic anaphase, the chromatids migrate from the metaphase plate towards the poles of the cell.

**Final Answer**: During mitotic anaphase, chromatids migrate from the metaphase plate towards the poles.

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