Cells in `G_(0)`-stage-

Options

A. Are metabolically more active
B. Are metabolically inactive
C. Remain metabolically active but no longer proliferate in normal condition
D. None

Answer

### Step-by-Step Text Solution:

1. **Understanding the Cell Cycle**: The cell cycle consists of several phases: G1 (Gap 1), S (Synthesis), G2 (Gap 2), and M (Mitosis). Each phase has specific functions related to cell growth and division.

2. **Introduction to G0 Phase**: The G0 phase is a resting or quiescent stage where cells exit the active cell cycle. Cells in this phase are not actively preparing to divide.

3. **Characteristics of G0 Stage**:
- **Metabolic Activity**: Cells in the G0 phase remain metabolically active. This means they continue to perform their regular functions and maintain cellular processes.
- **Non-Division**: Despite being metabolically active, these cells do not undergo division. They are in a state of rest and do not progress through the cell cycle.

4. **Re-entry into the Cell Cycle**: Cells in G0 can re-enter the cell cycle under certain conditions. Factors such as growth signals or specific environmental cues can trigger these cells to resume division.

5. **Examples of G0 Cells**: Many differentiated cells, such as nerve cells and muscle cells, can enter the G0 phase. These cells may remain in G0 for extended periods or even indefinitely.