During mitotic anaphase, chromatids migrate-

Options

A. From the poles of the cell toward the metaphasic plate
B. Toward the NM
C. Along with their side chromatids toward one pole
D. From metaphase plate towards the poles

Answer

**Step-by-Step Solution:**

1. **Understanding Mitosis**: Mitosis is the process of cell division that results in two identical daughter cells. It consists of several phases: prophase, metaphase, anaphase, and telophase.

2. **Identifying Anaphase**: During mitotic anaphase, the sister chromatids, which are the duplicated chromosomes, are separated and pulled apart. This phase follows metaphase, where chromosomes align at the metaphase plate.

3. **Chromatid Migration**: In anaphase, the centromeres that hold the sister chromatids together divide. Each chromatid is then pulled towards opposite poles of the cell. This movement is facilitated by the spindle fibers that are attached to the kinetochores.

4. **Role of Kinetochore**: The kinetochore is a protein structure on the chromosome that forms at the centromere. It serves as the attachment point for spindle fibers, which are responsible for pulling the chromatids apart during anaphase.

5. **Direction of Movement**: The chromatids migrate away from the metaphase plate towards the opposite poles of the cell. This ensures that each daughter cell will receive an identical set of chromosomes.

6. **Conclusion**: Therefore, during mitotic anaphase, chromatids migrate towards the opposite poles of the cell.

**Final Answer**: During mitotic anaphase, chromatids migrate towards the opposite poles of the cell.

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