One difference between mitosis and meiosis I is that-

Options

A. homologous chromosome pairs synapse during mitosis
B. Chromosome do not replicate in the interphase preceding meiosis.
C. Homologous chromosomes pairs synapse during meiosis but not mitosis.
D. Spindle composed of microtubules are not required during meiosis.

Answer

To answer the question regarding the difference between mitosis and meiosis I, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Mitosis**: Mitosis is a type of cell division that results in two daughter cells, each having the same number of chromosomes as the parent cell. It is primarily involved in growth, repair, and asexual reproduction.

2. **Understanding Meiosis I**: Meiosis I is the first division in the process of meiosis, which leads to the formation of gametes. It consists of two rounds of division and results in four daughter cells, each with half the number of chromosomes of the original cell.

3. **Key Processes in Meiosis I**: During Meiosis I, homologous chromosomes pair up in a process called synapsis. This occurs during prophase I, where homologous chromosomes align closely together and can exchange genetic material through a process called crossing over.

4. **Comparison of Synapsis**: In mitosis, homologous chromosomes do not pair up; instead, individual chromosomes line up during metaphase. There is no synapsis or crossing over in mitosis.

5. **Conclusion**: The main difference between mitosis and meiosis I is the presence of synapsis of homologous chromosomes during prophase I of meiosis, which does not occur in mitosis.

### Final Answer:
One difference between mitosis and meiosis I is that in meiosis I, homologous chromosomes undergo synapsis during prophase I, whereas in mitosis, there is no synapsis of homologous chromosomes.