Choose the correct option.

Options

A. Longest phase in meiosis is metaphase -1
B. During cell division spindles are attached to NOR (Nucleolar organising region) of chromosome
C. In meiosis nucleus divides twice and DNA also replicates twice
D. Synaptinemal complex appears first in zygotene of meiosis and disappears in diplotene

Answer

To solve the question, we need to analyze each of the provided options regarding meiosis and identify the correct one. Here’s a step-by-step breakdown:

### Step 1: Analyze Option 1
- **Statement**: In meiosis, the longest phase is Metaphase 1.
- **Evaluation**: This statement is incorrect. The longest phase of meiosis is actually Prophase 1, not Metaphase 1. Therefore, this option is not correct.

### Step 2: Analyze Option 2
- **Statement**: During cell division, spindles are attached to norov chromosomes, that is, nuclear-organizing reason.
- **Evaluation**: This statement is misleading. Spindle fibers attach to the kinetochores of chromosomes, which are located at the centromere. The term "norov chromosomes" is not standard terminology in biology. Therefore, this option is also incorrect.

### Step 3: Analyze Option 3
- **Statement**: In meiosis, the nucleus divides twice and DNA also replicates twice.
- **Evaluation**: This statement is partially true. While it is correct that the nucleus divides twice in meiosis, DNA replication occurs only once during the S phase of interphase before meiosis begins. Therefore, this option is incorrect.

### Step 4: Analyze Option 4
- **Statement**: The synaptonemal complex appears for the first time in zygotene of meiosis and disappears in diplotene.
- **Evaluation**: This statement is correct. The synaptonemal complex forms during the zygotene stage of prophase 1 in meiosis, facilitating the pairing of homologous chromosomes, and it disappears during the diplotene stage. Therefore, this option is correct.

### Conclusion
After analyzing all the options, the correct answer is **Option 4**.

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