I. Proton channel of oxysome / complex V / ATP synthase is located in `F_(0)`
II. Metabolic water is water produced in terminal oxidation / produced in respiration
III. CoQ accept electron from NADH dehydrogenase (complex) and also can accept electron from `FADH_(2)` / succinate Q-reducatase / complex II
IV. Cytochrome c is a small protein attached to outer surface of the inner mitochondrial membrane and acts as a mobile carrier for transfer of electrons between complex III (Cyt bc, comlex) and IV
V. Complex IV refers to cytochorme c oxidase (cyta a,`a_(3)` and 2 Cu per centre)
VI. If a cell is treated with a drug that inhibits ATP synthase, the pH of mitochondrial matrix will increase

Options

A. All are correct
B. All are incorrect
C. I and V are correct
D. Only III is correct

Answer

To analyze the statements given in the question, we will evaluate each statement one by one.

### Step-by-Step Solution:

1. **Statement I: Proton channel of oxysome / complex V / ATP synthase is located in `F_(0)`**
- This statement is **True**. The F0 part of ATP synthase is indeed the proton channel where protons flow through, driving the synthesis of ATP.

2. **Statement II: Metabolic water is water produced in terminal oxidation / produced in respiration**
- This statement is **True**. Metabolic water is generated during cellular respiration, particularly during the electron transport chain, where oxygen acts as the final electron acceptor.

3. **Statement III: CoQ accepts electrons from NADH dehydrogenase (complex) and also can accept electrons from `FADH_(2)` / succinate Q-reductase / complex II**
- This statement is **True**. Coenzyme Q (CoQ) accepts electrons from both NADH dehydrogenase (Complex I) and FADH2 (Complex II).

4. **Statement IV: Cytochrome c is a small protein attached to the outer surface of the inner mitochondrial membrane and acts as a mobile carrier for transfer of electrons between complex III (Cyt bc, complex) and IV**
- This statement is **True**. Cytochrome c is indeed a small protein that transfers electrons between Complex III and Complex IV in the electron transport chain.

5. **Statement V: Complex IV refers to cytochrome c oxidase (cyta a, `a_(3)` and 2 Cu per centre)**
- This statement is **True**. Complex IV is known as cytochrome c oxidase and contains cytochromes a, a3, and copper centers.

6. **Statement VI: If a cell is treated with a drug that inhibits ATP synthase, the pH of mitochondrial matrix will increase**
- This statement is **True**. If ATP synthase is inhibited, protons will accumulate in the intermembrane space, leading to a decrease in proton concentration in the mitochondrial matrix, thus increasing the pH (making it more basic).

### Final Evaluation:
All statements (I to VI) are true based on the understanding of the electron transport chain and ATP synthesis in cellular respiration.