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Pepsin is -...

Pepsin is -

A

Inactive proteolytic gastric enzyme

B

Active proteolytic gastric enzyme

C

Active enzyme of pancreatic juice

D

Active lipolytic enzyme

Text Solution

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The correct Answer is:
**Step-by-Step Solution:** 1. **Understanding Pepsin**: Pepsin is an enzyme that plays a crucial role in the digestion of proteins in the stomach. 2. **Source of Pepsin**: Pepsin is produced in the stomach by specialized cells called peptic cells, which are part of the gastric glands. 3. **Formation of Pepsinogen**: The peptic cells secrete an inactive precursor known as pepsinogen. This is important because it prevents the enzyme from digesting the cells that produce it. 4. **Role of Hydrochloric Acid (HCl)**: The gastric glands also contain auxintic cells that secrete hydrochloric acid (HCl). When pepsinogen comes into contact with HCl, it undergoes a transformation. 5. **Activation of Pepsinogen**: The acidic environment created by HCl activates pepsinogen, converting it into its active form, pepsin. 6. **Function of Pepsin**: Once activated, pepsin acts as a proteolytic enzyme, meaning it breaks down proteins into smaller peptides, facilitating digestion. 7. **Conclusion**: Therefore, pepsin is classified as an active proteolytic gastric enzyme. **Final Answer**: Pepsin is an active proteolytic gastric enzyme. ---
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Molecular mass from osmotic pressure: Pepsin is an enzyme present in the human digestive tract. A solution of a 0.500 gram sample of purified pepsin in 30.0 mL of aqueous solution exhibits an osmotic pressure of 892 torr at 27^(@)C . Estimate the molecular mass of pepsin. Strategy: An enzyme is a protein that acts as a biological catalyst. Pepsin catalyzes the metabolic cleavage of amino acid chain (called peptide chains) in other proteins. To determine molecular mass, we must first find the number of moles (n) of pepsin represented by the 0.500 g sample. We can do this by first rearranging the equation pi=CRT for osmotic pressure to find the molarity of the pepsin solution and then multiplying it by the volume of the solution to obtain the number of moles of pepsin.

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