The glucose homeostasis in blood is maintained jointly by -

Options

A. Insulin and epinephrine
B. Insulin and nor- epinephrine
C. Insulin and glucagon
D. Glucagon and cortisol

Answer

To answer the question regarding which hormones jointly maintain glucose homeostasis in the blood, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Homeostasis**:
- Homeostasis refers to the process by which biological systems maintain stability while adjusting to conditions that are optimal for survival. In this context, it specifically relates to maintaining stable glucose levels in the blood.

2. **Identifying Key Hormones**:
- The two primary hormones involved in regulating blood glucose levels are **insulin** and **glucagon**.

3. **Role of Insulin**:
- Insulin is produced by the beta cells of the pancreas. When blood glucose levels rise (for example, after eating), insulin is released into the bloodstream. Insulin facilitates the uptake of glucose by cells and promotes the conversion of glucose to glycogen for storage in the liver and muscles, thereby lowering blood glucose levels.

4. **Role of Glucagon**:
- Glucagon is produced by the alpha cells of the pancreas. When blood glucose levels drop (for example, during fasting), glucagon is released. It stimulates the liver to convert glycogen back into glucose and release it into the bloodstream, thus increasing blood glucose levels.

5. **Antagonistic Action**:
- Insulin and glucagon have opposing effects on blood glucose levels. Insulin lowers blood glucose, while glucagon raises it. This antagonistic relationship helps to maintain glucose homeostasis.

6. **Conclusion**:
- Therefore, the hormones that jointly maintain glucose homeostasis in the blood are **insulin and glucagon**.

### Final Answer:
The glucose homeostasis in blood is maintained jointly by **insulin and glucagon**.