In order for all a cell to be responsive to a lipid - soluble hormone, it must have -

Options

A. G – protein
B. `cAMP`
C. A specific intracellular receptor
D. A specific cell surface receptor

Answer

To determine what a cell must have in order to be responsive to a lipid-soluble hormone, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Lipid-Soluble Hormones**:
- Lipid-soluble hormones, such as steroid hormones (e.g., estrogen, progesterone, testosterone), can easily cross the cell membrane due to their hydrophobic nature.

2. **Identify the Receptor Location**:
- Since lipid-soluble hormones can cross the cell membrane, their receptors are located inside the cell, specifically in the cytoplasm or nucleus. These are known as intracellular receptors.

3. **Differentiate from Water-Soluble Hormones**:
- In contrast, water-soluble hormones (like peptide hormones) bind to receptors on the cell surface and utilize secondary messengers (like cyclic AMP) to relay their signals inside the cell.

4. **Conclusion**:
- For a cell to be responsive to lipid-soluble hormones, it must have specific intracellular receptors that can bind to these hormones once they have crossed the cell membrane.

5. **Final Answer**:
- Therefore, the correct answer is that a cell must have **specific intracellular receptors** to be responsive to lipid-soluble hormones.