Go through the following statements :
I. Silicosis is the result of exposure to silica that causes permanent lung damage and death
II. Transportation of gases and digested food materials in the body of higher animals causes muscle weakness and fatigue
III. ADH is a neurohpophysial hormone that regulates body water
IV. Myasthenia gravis is a neuromuscular disease that is mediated by circulatory system
Which of the following statement (s) is/are correct ?

Options

A. I and II are correct
B. II and III and correct
C. II and IV
D. I, III and IV are correct

Answer

To determine which statements are correct, let's analyze each statement one by one:

### Step 1: Analyze Statement I
**Statement I:** Silicosis is the result of exposure to silica that causes permanent lung damage and death.

- **Analysis:** Silicosis is indeed a lung disease caused by inhaling fine silica dust. It leads to inflammation and scarring of the lung tissue, which can result in permanent lung damage and can be fatal.
- **Conclusion:** **This statement is correct.**

### Step 2: Analyze Statement II
**Statement II:** Transportation of gases and digested food materials in the body of higher animals causes muscle weakness and fatigue.

- **Analysis:** The transportation of gases (like oxygen and carbon dioxide) and digested food materials (like glucose) is essential for cellular respiration and energy production in the body. If these processes are impaired, it could lead to muscle weakness and fatigue; however, the statement implies that the transportation itself causes weakness and fatigue, which is misleading.
- **Conclusion:** **This statement is incorrect.**

### Step 3: Analyze Statement III
**Statement III:** ADH is a neurohypophysial hormone that regulates body water.

- **Analysis:** Antidiuretic hormone (ADH), also known as vasopressin, is produced in the hypothalamus and released from the posterior pituitary (neurohypophysis). It plays a crucial role in regulating water balance in the body by promoting water reabsorption in the kidneys.
- **Conclusion:** **This statement is correct.**

### Step 4: Analyze Statement IV
**Statement IV:** Myasthenia gravis is a neuromuscular disease that is mediated by the circulatory system.

- **Analysis:** Myasthenia gravis is an autoimmune disorder that affects the neuromuscular junction, leading to weakness in voluntary muscles. It is caused by antibodies that block or destroy nicotinic acetylcholine receptors at the neuromuscular junction, not directly mediated by the circulatory system.
- **Conclusion:** **This statement is incorrect.**

### Final Conclusion
Based on the analysis:
- **Correct Statements:** I and III
- **Incorrect Statements:** II and IV

Thus, the correct statements are **I and III**.

### Summary of Correct Statements:
- Statement I is correct.
- Statement II is incorrect.
- Statement III is correct.
- Statement IV is incorrect.

### Final Answer:
**The correct statements are I and III.**

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