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Under which of the following conditions ...

Under which of the following conditions appreciable amount of glucose does not appear in the urine?
a. Glucose concentration exceeds renal threshold value
b. Diabetes mellitus.
c. Diabetes insipidus.
d. Glucose concentration exceeds 180 mg/ 100 ml of blood

A

a & c only

B

b & d only

C

c only

D

a, b & d only

Text Solution

AI Generated Solution

The correct Answer is:
To determine under which condition an appreciable amount of glucose does not appear in the urine, we will analyze each option provided in the question: 1. **Option A: Glucose concentration exceeds renal threshold value** - The renal threshold for glucose is typically around 180 mg/dL. When blood glucose levels exceed this threshold, the kidneys cannot reabsorb all the glucose, leading to glucose appearing in the urine. Therefore, this condition does not prevent glucose from appearing in the urine. 2. **Option B: Diabetes mellitus** - In diabetes mellitus, the body either does not produce enough insulin or the cells do not respond to insulin effectively. This leads to high blood glucose levels, which exceed the renal threshold, resulting in glucose spilling into the urine. Hence, this condition also does not prevent glucose from appearing in the urine. 3. **Option C: Diabetes insipidus** - Diabetes insipidus is a condition characterized by an imbalance of fluids in the body, leading to excessive urination (polyuria) but does not involve glucose metabolism. In this condition, the glucose levels in the blood remain normal, and thus, glucose does not appear in the urine. Therefore, this condition is the correct answer as it does not lead to glucose in the urine. 4. **Option D: Glucose concentration exceeds 180 mg/100 ml of blood** - Similar to option A, if glucose concentration exceeds 180 mg/dL, it indicates that the renal threshold has been surpassed, and glucose will appear in the urine. Thus, this option does not prevent glucose from being present in the urine. **Conclusion:** The correct answer is **C. Diabetes insipidus**, as this condition does not result in appreciable amounts of glucose appearing in the urine.
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