When glomerular filtration rate (i)______, the juxtaglomerular cells are stimulated to release (ii)______ to regulate the filtration rate.

Options

A. i-rises, ii-rennin
B. i-rises, ii-renin
C. i-falls, ii-rennin
D. i-falls, ii-renin

Answer

To solve the question, we need to fill in the blanks with the appropriate terms related to the glomerular filtration rate (GFR) and the response of juxtaglomerular cells.

### Step-by-Step Solution:

1. **Understanding Glomerular Filtration Rate (GFR)**:
- The glomerular filtration rate is a measure of how well the kidneys filter blood. It indicates the volume of fluid filtered from the renal glomerular capillaries into the Bowman's capsule per unit time.

2. **Identifying the Condition**:
- The question states, "When glomerular filtration rate (i)______." We know that a decrease in GFR typically occurs when blood pressure drops. Therefore, we can fill in the first blank with "decreases" or "falls".

3. **Response of Juxtaglomerular Cells**:
- The juxtaglomerular cells are specialized cells in the kidneys that respond to changes in blood pressure and GFR. When GFR decreases, these cells are stimulated to release a hormone.

4. **Identifying the Hormone Released**:
- The hormone released by the juxtaglomerular cells is "renin". Renin plays a crucial role in the regulation of blood pressure and fluid balance.

5. **Final Answer**:
- Thus, the complete sentence would be: "When glomerular filtration rate (i) **decreases**, the juxtaglomerular cells are stimulated to release (ii) **renin** to regulate the filtration rate."