What is amniocentesis?
I. A pre-natal, foetal determination test.
II. A post-natal foetal determination test
Ill. It is based on the chromosomal pattern of the amniotic fluid.
IV. It is based on the chromosomal pattern of the chorionic fluid.
V. It is based on the chromosomal pattern of the amniotic fluid and the seminal fluid

Options

A. II, III
B. I, V
C. I, III
D. l, V

Answer

### Step-by-Step Solution

1. **Definition of Amniocentesis**: Amniocentesis is a medical procedure used primarily for prenatal diagnosis of chromosomal abnormalities and fetal sex determination. It involves the extraction of amniotic fluid surrounding the fetus.

2. **Understanding the Options**:
- **Option I**: "A pre-natal, foetal determination test."
- This is correct. Amniocentesis is performed during pregnancy (prenatal) to determine various conditions related to the fetus.

- **Option II**: "A post-natal foetal determination test."
- This is incorrect. Amniocentesis is not performed after birth (postnatal).

- **Option III**: "It is based on the chromosomal pattern of the amniotic fluid."
- This is correct. The test analyzes the chromosomal pattern found in the amniotic fluid to identify genetic disorders or the sex of the fetus.

- **Option IV**: "It is based on the chromosomal pattern of the chorionic fluid."
- This is incorrect. Amniocentesis specifically uses amniotic fluid, not chorionic fluid.

- **Option V**: "It is based on the chromosomal pattern of the amniotic fluid and the seminal fluid."
- This is incorrect. Amniocentesis only involves amniotic fluid; seminal fluid is not used in this procedure.

3. **Conclusion**: Based on the analysis of the options, the correct statements regarding amniocentesis are:
- I (A pre-natal, foetal determination test) is correct.
- III (It is based on the chromosomal pattern of the amniotic fluid) is also correct.
- Therefore, the correct answers are I and III.