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Haemophilia is a condition in which bloo...

Haemophilia is a condition in which blood fails to clot or clots only very slowly. Studies of this human sex-linked trait show that

A

every X chromosome carries the dominant allele.

B

a Y chromosome never carries the dominant allele.

C

both X and Y chromosomes can bear the recessive allele.

D

neither X nor Y chromosomes can bear the recessive allele.

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### Step-by-Step Solution: 1. **Understanding Hemophilia**: Hemophilia is a genetic disorder characterized by the inability of blood to clot properly. This condition is primarily linked to the X chromosome. 2. **Genetic Basis**: The gene responsible for hemophilia is located on the X chromosome. There are two types of alleles for this gene: - Normal allele (represented as X) - Defective allele (represented as XH) 3. **Genotypes in Females**: Females have two X chromosomes (XX). The possible genotypes for females regarding hemophilia are: - Normal (XX) - Carrier (XHX) - Hemophilic (XHXH) 4. **Genotypes in Males**: Males have one X and one Y chromosome (XY). The possible genotypes for males regarding hemophilia are: - Normal (XY) - Hemophilic (XHY) 5. **Inheritance Patterns**: Since males have only one X chromosome, if they inherit the defective allele (XH), they will express hemophilia. Females can be carriers or affected depending on whether they inherit one or two defective alleles. 6. **Evaluating Statements**: Based on the understanding of hemophilia and its genetic basis, we can evaluate the statements: - **Statement 1**: Every X chromosome carries the dominant allele. (Incorrect) - **Statement 2**: A Y chromosome never carries the dominant allele. (Correct) - **Statement 3**: Both X and Y chromosomes can bear the recessive allele. (Incorrect) - **Statement 4**: Neither X nor Y chromosome can bear the recessive allele. (Incorrect) 7. **Conclusion**: The correct statement based on the observations is that the Y chromosome never carries the dominant allele.
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Knowledge Check

  • Heredity disease condition in which the blood fails to coagulate

    A
    Sickle cell anemia
    B
    Leukemia
    C
    Haemophilia
    D
    Alkaptonuria
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    Down 's syndrome
    B
    Colour blindness
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    Curly hair
    D
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  • Which of the following traits in human is sex linked ?

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    Diabetes
    B
    Colour of eyes
    C
    Night blindness
    D
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