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Klinefelter's syndrome results from the ...

Klinefelter's syndrome results from the fusion of

A

an X egg and a YY sperm.

B

an XY egg and an X sperm.

C

an XX egg and a Y sperm.

D

an XX egg and a YY sperm.

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The correct Answer is:
### Step-by-Step Solution: 1. **Understanding Klinefelter's Syndrome**: Klinefelter's syndrome is a genetic condition that occurs in males and is characterized by the presence of an extra X chromosome. The typical chromosomal composition for Klinefelter's syndrome is 47,XXY instead of the normal 46,XY. 2. **Chromosomal Composition**: The chromosomal makeup of an individual with Klinefelter's syndrome is 44 autosomes and 2 sex chromosomes (XXY). This means that there are 44 chromosomes that are not sex chromosomes (autosomes) and 3 sex chromosomes (XXY). 3. **Fusion of Gametes**: Klinefelter's syndrome arises from the fusion of an egg and a sperm. The egg contributes one X chromosome, and the sperm contributes one X and one Y chromosome, leading to the XXY composition. 4. **Analyzing the Options**: - **Option 1**: N-Egg, N-A-Y-Y-Sperm - This suggests the presence of two Y chromosomes which is not characteristic of Klinefelter's syndrome. - **Option 2**: XY-Egg - This is incorrect as eggs do not carry Y chromosomes; they only carry X chromosomes. - **Option 3**: XX-Egg and Y-Sperm - This is the correct combination that results in Klinefelter's syndrome (XXY). - **Option 4**: 2X from egg and 2Y from sperm - This combination would not occur in Klinefelter's syndrome. 5. **Conclusion**: The correct answer is that Klinefelter's syndrome results from the fusion of an XX egg and a Y sperm, leading to the chromosomal composition of 44 + XXY.
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