Choose the correct incorrect option.

Options

A. Recombination and mutation are phenomenon that lead to variations in DNA.
B. Chromosomal aberrations are commonly observed in cancer cells
C. A change in a single base pair of DNA is not sufficient to cause mutation
D. Point mutation arises due to change in a single base pair

Answer

To solve the question of identifying the incorrect option among the given statements, let's analyze each option step by step.

### Step-by-Step Solution:

1. **Option 1: Recombination and variations, recombination and mutations are phenomena that lead to variation in DNA.**
- This statement is correct. Recombination and mutations are indeed processes that contribute to genetic variation.

2. **Option 2: Chromosomal abrasions are commonly observed in cancer cells.**
- This statement is also correct. Cancer cells often exhibit chromosomal abnormalities, including abrasions, which can lead to genetic instability.

3. **Option 3: Change in single base pair of DNA is not sufficient to cause mutation.**
- This statement is incorrect. A change in a single base pair can indeed lead to a mutation, such as a point mutation, which can affect protein function.

4. **Option 4: Point mutation arises due to change in single base pair.**
- This statement is correct. A point mutation specifically refers to a change in a single nucleotide base pair in the DNA sequence.

5. **Option 5: Recombination and recombination, recombination and recombination are caused due to change in single base pair of DNA.**
- This statement is incorrect and appears to be repetitive and confusing. Recombination is a process that involves the exchange of genetic material between chromosomes, which is not solely caused by a change in a single base pair.

### Conclusion:
The incorrect options are **Option 3** and **Option 5**. However, since the question asks for a single incorrect option, **Option 3** is the most straightforwardly incorrect statement.