Hybridomas are result of the fusion of

Options

A. normal antibody producing cell with myeloma
B. abnoramal antibody producing cell with myeloma
C. male reproductive cell with myeloma
D. female reproductive cell with myeloma

Answer

**Step-by-Step Solution:**

1. **Understanding Hybridomas**: Hybridomas are specialized cells that are created through the fusion of two different types of cells.

2. **Identifying the Cells Involved**: The two types of cells that fuse to form hybridomas are:
- **B Cells**: These are immune cells that produce antibodies. They are typically derived from the spleen of a mouse.
- **Myeloma Cells**: These are cancerous cells that have the ability to divide indefinitely (immortalized cells).

3. **The Fusion Process**: The fusion of these two cell types results in hybridomas. This process combines the antibody-producing capabilities of the B cells with the immortal nature of the myeloma cells.

4. **Outcome of Fusion**: The resulting hybridoma cells can produce a specific type of antibody continuously, which is useful for various applications, including research and therapeutic uses.

5. **Significance of Hybridomas**: Hybridomas are significant in the field of immunology and biotechnology because they allow for the production of monoclonal antibodies, which are antibodies that are identical and specific to a particular antigen.

**Final Answer**: Hybridomas are the result of the fusion of mouse spleen (B) cells and myeloma cells.

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