Which of the following diseases cause chronic inflammation in the lymphatic vessels of the lower limb that result into its massive swelling?

Options

A. ascariasis
B. filariasis
C. amoebiasis
D. trypanosomiasis

Answer

To answer the question regarding which disease causes chronic inflammation in the lymphatic vessels of the lower limb, resulting in massive swelling, we can follow these steps:

### Step 1: Identify the Disease
The disease that is commonly associated with chronic inflammation of the lymphatic vessels in the lower limb is **Lymphatic Filariasis**. This condition is caused by parasitic infections, primarily by filarial worms such as Wuchereria bancrofti.

### Step 2: Understand the Mechanism
In Lymphatic Filariasis, the filarial worms invade the lymphatic system, leading to blockage and inflammation of the lymphatic vessels. This obstruction prevents the normal flow of lymph fluid, resulting in the accumulation of fluid and subsequent swelling, known as lymphedema.

### Step 3: Recognize Symptoms
The primary symptom of Lymphatic Filariasis is massive swelling of the affected limb, often referred to as elephantiasis when it becomes severe. Other symptoms may include pain, recurrent infections, and skin changes.

### Step 4: Identify Causes
The main cause of Lymphatic Filariasis is the transmission of filarial parasites through mosquito bites. Poor sanitation and living in endemic areas can increase the risk of infection.

### Step 5: Conclusion
Thus, the disease that causes chronic inflammation in the lymphatic vessels of the lower limb leading to massive swelling is **Lymphatic Filariasis**.

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