In human body ,HIV attacks mainly

Options

A. B-lymphocytes
B. T-lymphocytes
C. antibodies
D. None of these

Answer

**Step-by-Step Solution:**

1. **Understanding HIV Entry**: When HIV (Human Immunodeficiency Virus) enters the human body, it targets specific cells to begin its replication process.

2. **Initial Target - Macrophages**: The first cells that HIV attacks are macrophages. These are a type of white blood cell that plays a crucial role in the immune system by engulfing pathogens and dead cells.

3. **Macrophages as HIV Factories**: Once HIV infects macrophages, these cells become 'factories' for the virus. The virus replicates within the macrophages, producing new viral particles.

4. **Subsequent Target - T Lymphocytes**: After replicating in macrophages, HIV then goes on to attack T lymphocytes, specifically the CD4+ T helper cells. These cells are vital for the immune response.

5. **Impact on Immune System**: The infection and subsequent destruction of T helper cells lead to a decrease in their count. This reduction results in immunodeficiency, making the individual more susceptible to infections and diseases.

6. **Conclusion**: Therefore, the main targets of HIV in the human body are macrophages and T lymphocytes, with a significant impact on the T helper cell count.

**Final Answer**: HIV attacks mainly macrophages and T lymphocytes, leading to a reduction in T helper cells.

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