Which of the following method(s) is/are used to introduce foreign DNA into host cells?

Options

A. biolistics
B. electrophoresis
C. elution
D. DNA ligation

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks about the methods used to introduce foreign DNA into host cells. This is a fundamental concept in biotechnology, particularly in genetic engineering.

2. **Identifying Methods**: There are several methods available for introducing foreign DNA into host cells. Some of the commonly known methods include:
- **Biolistics (Gene Gun)**: This method uses high-velocity microprojectiles to deliver DNA into cells. It is particularly useful for plant cells.
- **Electroporation**: This technique involves applying an electrical field to cells to increase the permeability of the cell membrane, allowing DNA to enter.
- **Microinjection**: This method involves directly injecting DNA into the nucleus of a cell using a fine glass needle.
- **Lipofection**: This technique uses liposomes to encapsulate DNA, which then fuses with the cell membrane to deliver the DNA into the cell.

3. **Conclusion**: The method specifically mentioned in the transcript is Biolistics, which is a form of gene transfer using a gene gun. However, it is important to note that there are other methods as well.

4. **Final Answer**: The methods used to introduce foreign DNA into host cells include Biolistics (gene gun), electroporation, microinjection, and lipofection.

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