A mouse in which one particular gene has been replaced by its inactivated form generated in vitro is called

Options

A. transgenic
B. knockout mouse
C. nude mouse
D. mutant mouse

Answer

**Step-by-Step Solution:**

1. **Understanding the Question**: The question asks about a specific type of mouse in which a particular gene has been replaced by its inactivated form. This indicates a genetic modification where the function of the gene is disrupted or removed.

2. **Identifying Key Terms**: The phrase "inactivated form" suggests that the gene is not functioning as it normally would. The term "generated in vitro" indicates that this modification was done in a controlled laboratory environment, rather than occurring naturally.

3. **Defining the Type of Mouse**: In genetic engineering, a mouse that has had a specific gene inactivated or replaced is commonly referred to as a "knockout mouse." This term is used to describe genetically modified organisms where one or more genes have been deliberately disrupted or "knocked out."

4. **Understanding the Process**: The process of creating a knockout mouse involves introducing artificial DNA into the mouse's genome. This artificial DNA can replace the existing gene or disrupt its function, leading to the inactivation of that gene.

5. **Conclusion**: Based on the understanding of the terms and the process involved, the answer to the question is that a mouse in which one particular gene has been replaced by its inactivated form generated in vitro is called a "knockout mouse."

**Final Answer**: A mouse in which one particular gene has been replaced by its inactivated form generated in vitro is called a **knockout mouse**.

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