`{:(,"Column I",,"Column II"),(I.,"Biopiracy",(A),"Gene therapy"),(II.,"Retroviral vector",(B),"Ellegal removal of biological materials"),(III.,"Biopatent",(C),"Right granted for biological entities"),(IV.,"Kohler and Milstein",(D),"Monoclonal antibody"):}`

Options

A. I - B, II - A, III - D, IV - C
B. I - B, II - A, III - C, IV - D
C. I - B, II - C, III - A, IV - D
D. I - D, II - A, III - B, IV - C

Answer

To solve the matching question between Column I and Column II, we will analyze each term in Column I and find the corresponding term in Column II.

### Step-by-Step Solution:

1. **Identify Biopiracy**:
- Biopiracy refers to the illegal removal of biological materials without permission or compensation to the indigenous communities that have traditionally used them.
- **Match**: Biopiracy (I) → Illegal removal of biological materials (B)

2. **Identify Retroviral Vector**:
- A retroviral vector is a tool used in gene therapy to deliver genetic material into cells. It modifies the genome permanently.
- **Match**: Retroviral vector (II) → Gene therapy (A)

3. **Identify Biopatent**:
- A biopatent is a right granted for biological entities, allowing the patent holder to control the use of a particular biological discovery or resource.
- **Match**: Biopatent (III) → Right granted for biological entities (C)

4. **Identify Kohler and Milstein**:
- Kohler and Milstein are known for their development of monoclonal antibodies, which are identical antibodies produced by cloned cells.
- **Match**: Kohler and Milstein (IV) → Monoclonal antibody (D)

### Final Matches:
- I → B: Biopiracy → Illegal removal of biological materials
- II → A: Retroviral vector → Gene therapy
- III → C: Biopatent → Right granted for biological entities
- IV → D: Kohler and Milstein → Monoclonal antibody

### Summary of Matches:
- I (Biopiracy) → B (Illegal removal of biological materials)
- II (Retroviral vector) → A (Gene therapy)
- III (Biopatent) → C (Right granted for biological entities)
- IV (Kohler and Milstein) → D (Monoclonal antibody)

---