Which of the following diseases is caused by hyposecretion of thyroxine in infants?

Options

A. Cushing's syndrome
B. Cretinism
C. Down's syndrome
D. Goitre

Answer

To determine which disease is caused by the hyposecretion of thyroxine in infants, we can analyze the options provided:

1. **Cushing's Syndrome**: This condition is characterized by an excess of cortisol in the body, not thyroxine. Therefore, this option is incorrect.

2. **Cretinism**: This disease is indeed caused by the hyposecretion of thyroxine (a thyroid hormone) in infants. It leads to impaired physical and mental development. Therefore, this option is correct.

3. **Down Syndrome**: This is a genetic disorder caused by a chromosomal defect (specifically, an extra copy of chromosome 21). It is not related to the secretion of thyroxine. Thus, this option is incorrect.

4. **Goiter**: This condition is primarily caused by iodine deficiency, which leads to an enlargement of the thyroid gland. It is not directly caused by the hyposecretion of thyroxine. Hence, this option is also incorrect.

Based on the analysis of the options, the correct answer is **Cretinism**, as it is the disease caused by the hyposecretion of thyroxine in infants.

**Final Answer**: Cretinism

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