A single stranded DNA or RNA, tagged with a radioactive molecule is called as__________and is allowed to hybridised to its complementary DNA in a clone of cells followed by detection using autoradiography.
Choose the option which correctly fills the blank

Options

A. Chimeric DNA
B. Recoñbinant DNA
C. Probe
D. Vector DNA

Answer

To solve the question, we need to identify the term that describes a single-stranded DNA or RNA tagged with a radioactive molecule, which is used for hybridization with complementary DNA.

### Step-by-Step Solution:

1. **Understanding the Terminology**: The question mentions a single-stranded DNA or RNA that is tagged with a radioactive molecule. This is a common technique used in molecular biology to detect specific sequences of nucleic acids.

2. **Identifying the Correct Term**: The term used to describe a single-stranded DNA or RNA that has been labeled (in this case, with a radioactive molecule) is known as a "probe". Probes are used to hybridize with complementary sequences in DNA or RNA.

3. **Hybridization Process**: The probe is allowed to hybridize to its complementary DNA in a clone of cells. This means that the probe will bind to the specific sequence that matches its own.

4. **Detection Method**: After hybridization, the detection of the bound probe is performed using autoradiography. This technique allows visualization of the radioactive signals emitted by the probe, indicating the presence of the complementary DNA.

5. **Final Answer**: Therefore, the correct term to fill in the blank is "probe".