ADH is synthesised by `"_________________"`, released by `"______________"` and acts on `"________________"`.

Options

A. Hypothalamus,neurohypophysis, PCT
B. Hypothalamus,neurohypophysis, DCT and collecting duct
C. Hypothalamus, adeonohypophysis, PCT
D. Hypothalamus, adenohypophysis, loop of Henly

Answer

To answer the question regarding the synthesis, release, and action of ADH (Antidiuretic Hormone), we can break it down into three parts:

1. **Synthesis of ADH**:
- ADH is synthesized in the **hypothalamus**. The hypothalamus is a region of the brain that plays a crucial role in hormone production and regulation of various bodily functions.

2. **Release of ADH**:
- After synthesis, ADH is transported to and released from the **neurohypophysis**, which is the posterior lobe of the pituitary gland. This part of the pituitary gland stores and releases hormones produced by the hypothalamus.

3. **Action of ADH**:
- ADH primarily acts on the **distal convoluted tubules (DCT)** and the **collecting ducts** of the nephron in the kidneys. Its main function is to promote water reabsorption, thereby concentrating the urine and reducing water loss from the body.

Putting it all together, the complete answer is:
ADH is synthesized by **hypothalamus**, released by **neurohypophysis**, and acts on **distal convoluted tubules and collecting ducts**.