Which of the following set of hormones are supposed to have intracellular receptors?

Options

A. Estrogen, testosterone, aldosterone
B. Thyroxine, insulin, glucagon
C. Epinephrine, cortisol, ADH
D. Oxytocin, glucagon, insulin

Answer

To determine which set of hormones have intracellular receptors, we need to understand the characteristics of the hormones and their solubility.

### Step-by-Step Solution:

1. **Understanding Intracellular Receptors**:
- Intracellular receptors are typically associated with lipid-soluble hormones. These hormones can easily pass through the cell membrane due to their solubility in lipids.

2. **Identifying Lipid-Soluble Hormones**:
- Common examples of lipid-soluble hormones include steroid hormones such as estrogen, testosterone, and aldosterone. These hormones can cross the cell membrane and bind to receptors inside the cell.

3. **Analyzing the Options**:
- **Option A**: Estrogen, Testosterone, and Aldosterone
- All three are steroid hormones and lipid-soluble. Therefore, they are expected to have intracellular receptors.
- **Option B**: Thyroxine, Insulin, and Glucagon
- Thyroxine is lipid-soluble and can have intracellular receptors, but insulin and glucagon are peptide hormones that are not lipid-soluble and bind to membrane-bound receptors.
- **Option C**: Cortisol and ADH
- Cortisol is lipid-soluble and has intracellular receptors, but ADH (Antidiuretic Hormone) is a peptide hormone that binds to membrane-bound receptors.

4. **Conclusion**:
- The only option that contains all hormones with intracellular receptors is **Option A**: Estrogen, Testosterone, and Aldosterone.

### Final Answer:
The correct set of hormones that are supposed to have intracellular receptors is **Option A: Estrogen, Testosterone, and Aldosterone**.