A large quantity of monoclonal antibodies are produced from

Options

A. B-Cells
B. Myeloma cells
C. Hybridoma cells
D. T-Lymphocytes

Answer

To solve the question, "A large quantity of monoclonal antibodies are produced from," we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Monoclonal Antibodies**:
- Monoclonal antibodies are identical antibodies produced from a single clone of B cells. They are specific to a particular antigen.

2. **Hybridoma Technology**:
- The production of monoclonal antibodies is primarily achieved through a technique known as hybridoma technology. This involves the fusion of specific B cells with myeloma cells.

3. **Immune Response in Mice**:
- To produce these antibodies, a mouse is immunized with a specific antigen. This stimulates the mouse's immune system to produce B cells that generate antibodies against that antigen.

4. **Isolation of B Cells**:
- After the immune response is elicited, B cells are harvested from the spleen of the immunized mouse. These B cells are responsible for producing the desired antibodies.

5. **Fusion with Myeloma Cells**:
- The isolated B cells are then fused with immortal myeloma cells (cancerous B cells that can divide indefinitely). This fusion creates hybridoma cells.

6. **Production of Monoclonal Antibodies**:
- The hybridoma cells are capable of producing large quantities of monoclonal antibodies. Each hybridoma cell will produce antibodies that are identical, as they originate from the same parent B cell.

7. **Conclusion**:
- Therefore, the correct answer to the question is that a large quantity of monoclonal antibodies are produced from **hybridoma cells**.

### Final Answer:
- The correct option is **C. Hybridoma cells**.

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