### Step-by-Step Solution:
1. **Understanding Enzymes**:
- Enzymes are biological catalysts that speed up chemical reactions in living organisms. Most enzymes are proteins.
2. **Identifying Ribozymes**:
- Ribozymes are a specific type of enzyme that are not proteins but are made of RNA (ribonucleic acid).
3. **Function of Ribozymes**:
- Ribozymes have catalytic activity, meaning they can facilitate biochemical reactions, similar to traditional enzymes.
4. **Evaluating Options**:
- **Option A**: "Enzymes which use ribose as substrates" - This is incorrect because ribozymes are not defined by using ribose; they are RNA molecules themselves.
- **Option B**: "Enzymes working on DNA" - This is incorrect because ribozymes are RNA molecules, not enzymes that act on DNA.
- **Option C**: "Nucleic acid with enzymatic activity" - This is correct because ribozymes are RNA molecules that have catalytic properties.
- **Option D**: "Enzyme RNA complexes" - This is incorrect because ribozymes are not complexes; they are RNA molecules that function as enzymes.
5. **Conclusion**:
- The correct answer is that ribozymes are "nucleic acid with enzymatic activity."
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