Generally accepted features of the biological membrane include all of the following, except

Options

A. Asymmetric arrangement of lipids
B. Rapid diffusion of inorganic ions across lipid bilayer
C. It comprises of both intrinsic and extrinsic proteins
D. Lateral diffusion of integral and peripheral proteins

Answer

To solve the question regarding the generally accepted features of biological membranes, we need to analyze each option provided and determine which one does not align with the known characteristics of biological membranes.

### Step-by-Step Solution:

1. **Understanding the Question**: The question asks us to identify which feature is NOT generally accepted as a characteristic of biological membranes.

2. **Analyzing Option 1**:
- **Statement**: Asymmetric arrangement of lipids.
- **Explanation**: Biological membranes exhibit an asymmetric distribution of lipids, meaning that the types and amounts of lipids differ between the inner and outer layers of the membrane. This is a well-established feature.
- **Conclusion**: This statement is correct and does not answer our question.

3. **Analyzing Option 2**:
- **Statement**: Rapid diffusion of inorganic ions across the lipid bilayer.
- **Explanation**: Inorganic ions typically do not diffuse rapidly across the lipid bilayer due to their charge and size. Instead, they often require specific transport proteins to facilitate their movement across the membrane.
- **Conclusion**: This statement is incorrect regarding the features of biological membranes, making it a potential answer to our question.

4. **Analyzing Option 3**:
- **Statement**: Comprises both intrinsic and extrinsic proteins.
- **Explanation**: Biological membranes contain both intrinsic (integral) proteins that span the membrane and extrinsic (peripheral) proteins that are attached to the surface. This is a recognized characteristic of biological membranes.
- **Conclusion**: This statement is correct and does not answer our question.

5. **Analyzing Option 4**:
- **Statement**: Lateral diffusion of integral and peripheral proteins.
- **Explanation**: Integral and peripheral proteins can move laterally within the membrane, which is a characteristic feature of the fluid mosaic model of membranes.
- **Conclusion**: This statement is also correct and does not answer our question.

6. **Final Conclusion**: Based on the analysis, the feature that is NOT generally accepted as a characteristic of biological membranes is **Option 2: Rapid diffusion of inorganic ions across the lipid bilayer**.

### Answer:
The correct answer is **Option 2**.