Which of the following factors will not cause change in gene frequency ?

Options

A. Mutation
B. gene flow
C. Large population
D. Genetic recombination

Answer

To solve the question "Which of the following factors will not cause change in gene frequency?", we will analyze each option provided:

1. **Mutation**:
- Mutations are random and inheritable changes in the DNA sequence. They introduce new alleles into a population, leading to changes in gene frequency. Therefore, mutation does cause a change in gene frequency.

2. **Gene Flow**:
- Gene flow refers to the transfer of genetic material (alleles) between populations through migration. When individuals move from one population to another and breed, they introduce new alleles, which can alter the gene frequency in both populations. Hence, gene flow does cause a change in gene frequency.

3. **Large Population**:
- A large population does not inherently change gene frequency. In fact, larger populations can maintain genetic stability and reduce the impact of genetic drift, which is a random change in allele frequency. Therefore, a large population itself does not cause a change in gene frequency.

4. **Genetic Recombination**:
- Genetic recombination occurs during meiosis when homologous chromosomes exchange genetic material. This process creates new combinations of alleles but does not change the overall gene frequency in the population. It simply reshuffles existing alleles. Thus, genetic recombination does not cause a change in gene frequency.

Based on the analysis above, the correct answer is:
**Large Population** (Option 3) will not cause a change in gene frequency.