There is a tRNA with anticodon UAC. If we apply the wobble hypothesis , then this tRNA can decode which of these codons ?

Options

A. It can decode AUG, AUG, AUU, AUA
B. It can decode AUG and AUC but not AUU and AUA
C. It can decode AUG but not AUC, AUU and AUA
D. It cannot decode any one of these codons AUG,AUG,AUU and AUA

Answer

To solve the question regarding the tRNA with the anticodon UAC and its ability to decode certain codons based on the wobble hypothesis, we can follow these steps:

### Step-by-Step Solution:

1. **Identify the Anticodon**: The given tRNA has the anticodon UAC.

2. **Determine the Corresponding Codon**: According to the genetic code, the codon that pairs with the anticodon UAC is AUG. This is because the first position of the codon can pair with the third position of the anticodon due to the wobble hypothesis.

3. **Understand the Wobble Hypothesis**: The wobble hypothesis states that the third base of the codon can be less specific in pairing with the anticodon. This means that a single tRNA can recognize multiple codons that code for the same amino acid.

4. **Identify Possible Codons**: The codon AUG codes for Methionine (Met) and is also the start codon. The tRNA with anticodon UAC can also pair with other codons due to the wobble effect. The codons that can be decoded by UAC include:
- AUG (Methionine)
- AUC (Isoleucine)
- AUU (Isoleucine)

5. **Conclusion**: Based on the wobble hypothesis, the tRNA with anticodon UAC can decode the codons AUG, AUC, and AUU.

### Final Answer:
The tRNA with anticodon UAC can decode the codons AUG, AUC, and AUU.