Restriction endonuclease HindII acts on a palindromic specific sequence of ..........base pair.

Options

A. 2
B. 4
C. 6
D. 8

Answer

To solve the question regarding the restriction endonuclease HindII and its action on a palindromic specific sequence, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Restriction Endonucleases**:
- Restriction endonucleases, also known as restriction enzymes, are proteins that cut DNA at specific sequences. They are crucial tools in molecular biology for DNA manipulation.

**Hint**: Remember that these enzymes recognize specific sequences in the DNA to make cuts.

2. **Identify the Specificity of HindII**:
- HindII is a specific type of restriction endonuclease. It is important to know which organism it was isolated from and its recognition sequence.

**Hint**: HindII was first discovered in the bacterium Haemophilus influenzae.

3. **Determine the Recognition Sequence**:
- The recognition sequence for HindII is a palindromic sequence. A palindromic sequence reads the same forwards and backwards, which is a common feature of many restriction sites.

**Hint**: Look for the term "palindromic" in the context of DNA sequences; it indicates symmetry.

4. **Count the Base Pairs**:
- HindII recognizes and cuts a specific sequence of 6 base pairs. This means that the enzyme will bind to a sequence that is 6 nucleotides long.

**Hint**: The question asks for the number of base pairs, so focus on the length of the recognition sequence.

5. **Select the Correct Answer**:
- Given the options (2, 4, 6, 8), and knowing that HindII acts on a palindromic specific sequence of 6 base pairs, the correct answer is 6.

**Hint**: Always verify the answer against the known characteristics of the enzyme.

### Final Answer:
Restriction endonuclease HindII acts on a palindromic specific sequence of **6 base pairs**.

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