Which one of the following statement is not correct about once-a-week pill for females?

Options

A. It is Saheli oral contraceptive pills for females developed by scientists of CDRI , Lucknow .
B. It is newly discovered contraceptive pills to be taken orally having progesterone - estrogen hormone combination.
C. It is with very few side effects and having high contraceptive value.
D. It prevents Implantation by changing the nature. Of endometrium of uterus.

Answer

To solve the question regarding the once-a-week pill for females, we need to analyze each statement provided about the pill, known as Saheli, and identify which one is not correct.

### Step-by-Step Solution:

1. **Understanding Saheli**:
- Saheli is an oral contraceptive pill developed by scientists at the Central Drug Research Institute (CDRI) in Lucknow, India. It is designed to be taken once a week.

2. **Evaluating the Statements**:
- **Statement 1**: "It is Saheli oral contraceptive pill for females developed by scientists of CDRI Lucknow."
- This statement is **correct**. Saheli is indeed developed by CDRI in Lucknow.

- **Statement 2**: "It is a newly discovered contraceptive pill to be taken orally having progesterone, estrogen hormone combination."
- This statement is **incorrect**. Saheli does not contain a combination of progesterone and estrogen. Instead, it contains a synthetic progestin and centchromone, which is a non-steroidal compound. Therefore, this statement is the one that is not correct.

- **Statement 3**: "It is having very few side effects and having high contraceptive value."
- This statement is **correct**. Saheli is known to have minimal side effects due to its non-steroidal nature and is effective as a contraceptive.

- **Statement 4**: "It prevents implantation by changing the nature of the endometrium of the uterus."
- This statement is **correct**. Saheli works by altering the endometrial lining, which prevents implantation even if fertilization occurs.

3. **Conclusion**:
- Based on the evaluation, the statement that is not correct about the once-a-week pill for females (Saheli) is the second statement regarding its hormonal composition.

### Final Answer:
The statement that is not correct about the once-a-week pill for females is:
"It is a newly discovered contraceptive pill to be taken orally having progesterone, estrogen hormone combination."