Which of the following is not synthesized by RNA polymerase III ?

Options

A. tRNA
B. snRNA
C. 5S rRNA
D. 5.8S rRNA

Answer

To solve the question "Which of the following is not synthesized by RNA polymerase III?" we need to analyze the options provided: RNA, SN RNA, 5S rRNA, and 5.8 S rRNA.

### Step-by-Step Solution:

1. **Understand the Role of RNA Polymerases**:
- In eukaryotic cells, there are three main types of RNA polymerases:
- **RNA Polymerase I**: Synthesizes most of the rRNA (except 5S rRNA).
- **RNA Polymerase II**: Synthesizes mRNA and some snRNA.
- **RNA Polymerase III**: Synthesizes tRNA, 5S rRNA, and other small RNAs.

2. **Identify the RNA Types**:
- **tRNA**: Transcribed by RNA Polymerase III.
- **5S rRNA**: Also transcribed by RNA Polymerase III.
- **snRNA (small nuclear RNA)**: Transcribed by RNA Polymerase II.
- **5.8S rRNA**: Transcribed by RNA Polymerase I.

3. **Determine Which is Not Synthesized by RNA Polymerase III**:
- From the analysis, we find that:
- **5S rRNA** is synthesized by RNA Polymerase III.
- **snRNA** is synthesized by RNA Polymerase II.
- **5.8S rRNA** is synthesized by RNA Polymerase I.
- Therefore, the option that is not synthesized by RNA Polymerase III is **5.8S rRNA**.

### Final Answer:
**5.8 S rRNA** is not synthesized by RNA polymerase III.