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Given below are the steps involved in th...

Given below are the steps involved in the citric cycle . Arrange them correct option.
i. Formation of alpha - ketoglutaric acid and succinyl - CoA.
ii. Condensation of acetyl group with oxaloacetic acid.
iii. Isomerization of citrate to isocitrate.
iv. Synthesis of GTP.

A

i,iv , iii , ii

B

iii, iv , ii ,i

C

iv, i, ii , iii

D

ii, iii, i, iv

Text Solution

AI Generated Solution

The correct Answer is:
To solve the problem of arranging the steps involved in the citric acid cycle, we need to understand the sequence of events that occur during this metabolic pathway. Here’s a step-by-step breakdown: ### Step-by-Step Solution: 1. **Identify the Steps**: The steps provided are: - i. Formation of alpha-ketoglutaric acid and succinyl-CoA. - ii. Condensation of acetyl group with oxaloacetic acid. - iii. Isomerization of citrate to isocitrate. - iv. Synthesis of GTP. 2. **Understanding the Citric Acid Cycle**: - The citric acid cycle (also known as the Krebs cycle or TCA cycle) begins with the condensation of acetyl-CoA with oxaloacetic acid to form citrate. - The first step is the condensation of acetyl group with oxaloacetic acid (Step ii). - Next, citrate is isomerized to isocitrate (Step iii). - Following this, isocitrate is converted into alpha-ketoglutaric acid and succinyl-CoA (Step i). - Finally, succinyl-CoA is converted to succinate, during which GTP is synthesized (Step iv). 3. **Arranging the Steps**: - Based on the sequence described: - First: ii. Condensation of acetyl group with oxaloacetic acid. - Second: iii. Isomerization of citrate to isocitrate. - Third: i. Formation of alpha-ketoglutaric acid and succinyl-CoA. - Fourth: iv. Synthesis of GTP. 4. **Final Arrangement**: The correct order of the steps in the citric acid cycle is: - ii → iii → i → iv ### Answer: The correct arrangement of the steps involved in the citric cycle is: **ii, iii, i, iv** ---
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