Excess of growth hormone causes acromegaly in adults . In normal individuals, such condition doesn't arise due to inhibition of growth hormone . Which of the following is responsible for secretion of hormone that regulates growth hormone secretion ?

Options

A. The gland situated at the base of diencephalon
B. The gland situated in a bony cavity of the sphenoid bone
C. The gland situated on the dorsal side of the forebrain
D. The gland having two lobes situated on either side of the trachea

Answer

To solve the question regarding which gland is responsible for the secretion of the hormone that regulates growth hormone secretion, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Growth Hormone Regulation**:
- Growth hormone (GH) is primarily regulated by the hypothalamus, which secretes hormones that stimulate or inhibit its release from the pituitary gland.

2. **Identifying the Glands**:
- The question provides several options regarding different glands:
- **Hypothalamus**: Located at the base of the diencephalon, it plays a crucial role in regulating various hormones, including growth hormone.
- **Pituitary Gland**: Located in the bony cavity of the sphenoid bone, it is responsible for secreting growth hormone but is not the gland that regulates its secretion.
- **Pineal Gland**: Situated on the dorsal side of the forebrain, it secretes melatonin and is not involved in growth hormone regulation.
- **Thyroid Gland**: Located on either side of the trachea, it secretes thyroxine and does not regulate growth hormone.

3. **Selecting the Correct Option**:
- From the options provided, the hypothalamus is the only gland that directly regulates the secretion of growth hormone by releasing growth hormone-releasing hormone (GHRH) and growth hormone-inhibiting hormone (GHIH).

4. **Conclusion**:
- Therefore, the correct answer to the question is the **hypothalamus**, as it is responsible for the secretion of hormones that regulate growth hormone secretion.

### Final Answer:
The gland responsible for the secretion of the hormone that regulates growth hormone secretion is the **hypothalamus**.

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