Carbonic anhydrase enzyme is present in .........., ……….. and for its activity the enzyme required...... as a cofactor.

Options

A. RBC, pancreatic cell and `Zn^(2+)`
B. Plasma,WBC and `Mn^(2+)`
C. RBC, plasma and `Ca^(2+)`
D. Laukocytes, macrophages and `Zn^(2+)`

Answer

To solve the question regarding the presence of the carbonic anhydrase enzyme and its required cofactor, we can break down the information step by step.

### Step-by-Step Solution:

1. **Identify the Locations of Carbonic Anhydrase:**
- Carbonic anhydrase is primarily found in red blood cells (RBCs). It is present in very high concentrations in these cells.
- It is also found in pancreatic cells, although in lesser amounts compared to RBCs.
- Additionally, minute quantities of carbonic anhydrase can be found in plasma.

2. **Determine the Required Cofactor:**
- For the activity of carbonic anhydrase, it requires a specific cofactor.
- The cofactor needed for carbonic anhydrase is zinc ion (Zn²⁺). This metal ion is essential for the enzyme's catalytic activity.

3. **Compile the Information:**
- Based on the above points, we can conclude that carbonic anhydrase is present in:
- Red blood cells (RBCs)
- Pancreatic cells
- The enzyme requires zinc ion as a cofactor for its activity.

### Final Answer:
Carbonic anhydrase enzyme is present in **RBCs**, **pancreatic cells**, and for its activity, the enzyme requires **zinc ion** as a cofactor.

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