Which of the following will produce adenosine triphosphate by substrate - level phosphorylation ?

Options

A. 2 - phoshoglycerate to 2 - phosphoenol pyruvate
B. Glucose to Glucose - 6 - phosphate
C. Phosphoenol pyruvic acid to pyruvic acid
D. Frutose 1 , 6 - biphosphate to PGAL and DHAP C

Answer

To solve the question of which of the following processes produces adenosine triphosphate (ATP) by substrate-level phosphorylation, we first need to understand what substrate-level phosphorylation is. This process involves the direct transfer of a phosphate group to adenosine diphosphate (ADP) to form ATP.

### Step-by-Step Solution:

1. **Understanding Substrate-Level Phosphorylation**:
- Substrate-level phosphorylation occurs when a phosphate group is directly transferred from a substrate to ADP, forming ATP. This process is distinct from oxidative phosphorylation, which occurs in the mitochondria.

2. **Identifying the Options**:
- The options provided are:
1. 2-phosphoglycerate to 2-phosphoenolpyruvate
2. Glucose to glucose 6-phosphate
3. Phosphoenolpyruvic acid to pyruvic acid
4. Fructose 1,6-bisphosphate to PGAL and DGDHAPC

3. **Analyzing Each Option**:
- **Option 1**: 2-phosphoglycerate to 2-phosphoenolpyruvate - This reaction does not involve ATP production.
- **Option 2**: Glucose to glucose 6-phosphate - This is an energy investment phase and does not produce ATP.
- **Option 3**: Phosphoenolpyruvic acid to pyruvic acid - This reaction is catalyzed by the enzyme pyruvate kinase and results in the production of ATP. This is a classic example of substrate-level phosphorylation.
- **Option 4**: Fructose 1,6-bisphosphate to PGAL and DGDHAPC - This reaction does not lead to ATP production.

4. **Conclusion**:
- The only reaction that produces ATP by substrate-level phosphorylation is **Option 3: Phosphoenolpyruvic acid to pyruvic acid**.

### Final Answer:
The correct option is **Option 3: Phosphoenolpyruvic acid to pyruvic acid**.