Klinefelter's syndrome can be easily identified by

Options

A. PCR
B. Karyotype
C. ELISA
D. RFLP

Answer

To solve the question regarding Klinefelter's syndrome and how it can be easily identified, we will go through the following steps:

### Step-by-Step Solution:

1. **Understand Klinefelter's Syndrome**:
- Klinefelter's syndrome is a genetic condition that occurs in males who have an extra X chromosome. This results in a total of 47 chromosomes instead of the typical 46. The karyotype for Klinefelter's syndrome is represented as 47,XXY.

**Hint**: Remember that Klinefelter's syndrome specifically involves males and an extra X chromosome.

2. **Identify the Methods of Detection**:
- There are various methods to identify genetic conditions, including:
- Polymerase Chain Reaction (PCR)
- Karyotyping
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Restriction Fragment Length Polymorphism (RFLP)

**Hint**: Familiarize yourself with different genetic testing methods and their purposes.

3. **Evaluate the Options**:
- **PCR**: This technique amplifies small segments of DNA but does not directly identify chromosomal abnormalities. Thus, it is not suitable for identifying Klinefelter's syndrome.
- **Karyotype**: This method involves arranging and analyzing chromosomes to identify abnormalities. It can clearly show the presence of an extra X chromosome, making it the correct method for identifying Klinefelter's syndrome.
- **ELISA**: This test detects antibodies and proteins, not chromosomal abnormalities, so it is not applicable here.
- **RFLP**: This technique analyzes DNA patterns but does not specifically identify chromosomal abnormalities related to Klinefelter's syndrome.

**Hint**: Focus on which method directly visualizes chromosome structure and number.

4. **Conclusion**:
- The correct answer to the question is **Karyotype**, as it allows for the identification of the extra X chromosome associated with Klinefelter's syndrome.

**Hint**: Always choose the method that directly relates to the type of genetic abnormality being investigated.

### Final Answer:
Klinefelter's syndrome can be easily identified by **Karyotype** analysis.