Select the one that is not related to osteoarthritis.

Options

A. In osteoarthritis, large weight - bearing joints are affected.
B. The articular cartilages get eroded.
C. It is a degenerative joint disease occurring in the late middle age.
D. It is caused due to excessive formation of uric acid.

Answer

To solve the question "Select the one that is not related to osteoarthritis," we will analyze each option provided and determine which statement does not pertain to osteoarthritis.

### Step-by-Step Solution:

1. **Understanding Osteoarthritis**:
- Osteoarthritis is a degenerative joint disease characterized by the breakdown of cartilage in joints, leading to pain and stiffness. It primarily affects weight-bearing joints such as the knees, hips, and spine.

2. **Analyzing the Options**:
- **Option 1**: "In osteoarthritis, large weight-bearing joints are affected."
- This statement is true. Osteoarthritis commonly affects large joints like the knees and hips.

- **Option 2**: "The articular cartilages get eroded."
- This statement is also true. A hallmark of osteoarthritis is the erosion of articular cartilage over time.

- **Option 3**: "It is a degenerative joint disease occurring in the late middle age."
- This statement is true as well. Osteoarthritis typically develops with age and is more prevalent in older adults.

- **Option 4**: "It is caused due to excessive formation of uric acid."
- This statement is false. Excessive formation of uric acid is related to gout, not osteoarthritis. Osteoarthritis is not caused by uric acid levels.

3. **Conclusion**:
- The statement that is not related to osteoarthritis is: "It is caused due to excessive formation of uric acid."

### Final Answer:
The correct option that is not related to osteoarthritis is: **"It is caused due to excessive formation of uric acid."**

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