Which named reaction is used to convert amides into amines

Options

A. Curtius reaction
B. Claisen condensation
C. Hoffmann reaction
D. Schimidt reaction

Answer

To solve the question of which named reaction is used to convert amides into amines, we will analyze the options provided and determine the correct reaction.

### Step-by-Step Solution:

1. **Understanding the Starting Material**:
- We start with an amide, which has the general structure R-C(=O)-NH2. Our goal is to convert this amide into an amine, R-NH2.

2. **Evaluating the Reactions**:
- **Curtius Reaction**:
- This reaction involves acyl azides, which are not amides. The reaction produces isocyanates and upon hydrolysis gives amines, but it does not start from an amide. Therefore, this is **not the correct option**.

- **Claisen Condensation**:
- This reaction involves the condensation of esters in the presence of a base. Since it does not involve amides at all, this is also **not the correct option**.

- **Hofmann Reaction**:
- The Hofmann reaction specifically involves the conversion of amides to primary amines. When an amide (R-C(=O)-NH2) is treated with bromine in the presence of NaOH, it results in a primary amine (R-NH2) and releases carbon dioxide. This reaction is indeed designed for converting amides to amines, making it the **correct option**.

- **Schmitt Reaction**:
- This reaction starts with carboxylic acids and involves the formation of amines, but it does not use amides as the starting material. Thus, this is also **not the correct option**.

3. **Conclusion**:
- After evaluating all the options, the only reaction that converts amides into amines is the **Hofmann reaction**.

### Final Answer:
The named reaction used to convert amides into amines is the **Hofmann reaction**.