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In erythroblastosis foetails,...

In erythroblastosis foetails,

A

Rh antibodies pass from the Rh(+ve) mother into the Rh(-ve) baby through the placenta .

B

Rh antibodies pass from the Rh(-ve) mother into the Rh(+ve) baby through the placenta.

C

Rh antigens pass from the Rh(-ve) mother into the Rh(+ve) baby through the placenta.

D

Rh antigens pass from the Rh(+ve) mother into the Rh(-ve) baby through the placenta.

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### Step-by-Step Solution: 1. **Understanding Erythroblastosis Fetalis**: - Erythroblastosis fetalis is a condition that occurs when an Rh-negative mother carries an Rh-positive fetus. This can lead to the mother’s immune system producing antibodies against the Rh factor. 2. **Rh Factor and Antibodies**: - The Rh factor is a protein that can be present on the surface of red blood cells. If an Rh-negative mother is exposed to Rh-positive blood (from her fetus), her immune system may recognize the Rh-positive cells as foreign and produce antibodies against them. 3. **First Pregnancy**: - In the first pregnancy, if the mother is Rh-negative and the baby is Rh-positive, the mother may not produce enough antibodies to harm the fetus. The antibodies are produced in low concentrations and typically do not cross the placenta in significant amounts. 4. **Subsequent Pregnancies**: - If the Rh-negative mother becomes pregnant again with another Rh-positive baby, her body has already been sensitized to the Rh factor from the first pregnancy. This means she will produce a higher concentration of antibodies against the Rh factor. 5. **Antibody Transfer**: - These antibodies can cross the placenta and enter the fetal circulation, where they can attack the Rh-positive red blood cells of the fetus, leading to hemolysis (destruction of red blood cells), anemia, and potentially fetal death. 6. **Conclusion**: - The correct statement regarding erythroblastosis fetalis is that Rh antibodies pass from the Rh-negative mother into the Rh-positive baby through the placenta. Therefore, the correct answer to the question is option number 2.
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