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Choose the correct statement/s regarding malaria :
(i) Malignant malaria is caused by plasmodium vivax .
(ii) Frequent chills and fever are caused by hemozoin.
(iii) Sporozoites reproduce sexually in hepatocytes.
(iv) Gametocyte develop in RBCs.

A

i and ii only

B

ii and iii only

C

iii and iv only

D

ii and iv only

Text Solution

AI Generated Solution

The correct Answer is:
To solve the question regarding malaria, we need to evaluate each statement provided: 1. **Statement (i): Malignant malaria is caused by Plasmodium vivax.** - **Evaluation**: This statement is incorrect. Malignant malaria is actually caused by *Plasmodium falciparum*, not *Plasmodium vivax*. Therefore, this statement is false. 2. **Statement (ii): Frequent chills and fever are caused by hemozoin.** - **Evaluation**: This statement is correct. Hemozoin is a toxic pigment produced during the digestion of hemoglobin by the malaria parasite. Its accumulation in the host's body can lead to symptoms such as chills and fever. Thus, this statement is true. 3. **Statement (iii): Sporozoites reproduce sexually in hepatocytes.** - **Evaluation**: This statement is incorrect. Sporozoites undergo asexual reproduction in the liver cells (hepatocytes) of the human host. Sexual reproduction occurs in the mosquito vector, not in the human host. Therefore, this statement is false. 4. **Statement (iv): Gametocytes develop in RBCs.** - **Evaluation**: This statement is correct. Gametocytes, which are the sexual forms of the malaria parasite, do develop in red blood cells (RBCs) of the human host. Thus, this statement is true. **Conclusion**: The correct statements regarding malaria are (ii) and (iv). ### Final Answer: The correct statements are: - (ii) Frequent chills and fever are caused by hemozoin. - (iv) Gametocytes develop in RBCs.
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