The synthesis of replisome takes place during which stage of the cell cycle ?

Options

A. `G_1` phase
B. `G_2` phase
C. S - phase
D. Interphase II

Answer

To determine during which stage of the cell cycle the synthesis of replisomes takes place, we can follow these steps:

### Step 1: Understand the Cell Cycle
The cell cycle consists of several phases: G1 (Gap 1), S (Synthesis), G2 (Gap 2), and M (Mitosis). Each phase has specific functions and processes.

### Step 2: Identify the Role of Replisomes
Replisomes are complexes responsible for DNA replication. They coordinate the process of copying DNA during cell division.

### Step 3: Determine When Replisomes are Synthesized
Replisomes are formed when the initiation complex is established. This occurs as the cell transitions from the G1 phase to the S phase.

### Step 4: Analyze the Phases
- **G1 Phase**: The cell grows and prepares for DNA synthesis. The initiation complex is formed here.
- **S Phase**: The actual DNA replication occurs, and the replisome is utilized during this phase.

### Step 5: Conclusion
Since the synthesis of replisomes occurs as the cell prepares for DNA replication and is utilized during the S phase, we conclude that the synthesis of replisomes takes place primarily during the G1 phase.

### Final Answer
The synthesis of replisomes takes place during the **G1 phase** of the cell cycle.

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