Which of the following layers in the wall of uterus does not undergo cyclical changes ?

Options

A. Perimetrium only
B. Myometrium only
C. Perimetrium and Myometrium
D. Endometrium only

Answer

To solve the question regarding which layer of the uterus wall does not undergo cyclical changes, we can follow these steps:

### Step 1: Identify the Layers of the Uterus
The uterus has three main layers:
1. **Perimetrium**: The outermost layer, which is a thin membranous layer.
2. **Myometrium**: The middle layer, which is thick and muscular, responsible for contractions during childbirth.
3. **Endometrium**: The innermost layer, which is glandular and has a rich supply of blood vessels.

**Hint**: Remember the three layers of the uterus: perimetrium (outer), myometrium (middle), and endometrium (inner).

### Step 2: Understand the Function of Each Layer
- The **perimetrium** serves as a protective layer and does not change during the menstrual cycle.
- The **myometrium** is involved in the contractions but remains structurally stable throughout the menstrual cycle.
- The **endometrium** is the layer that undergoes cyclical changes, thickening and shedding during the menstrual cycle.

**Hint**: Focus on which layer is involved in the menstrual cycle and which layers serve more structural or protective functions.

### Step 3: Determine Which Layer Does Not Change
From our understanding:
- The **endometrium** is the only layer that undergoes cyclical changes, such as thickening and shedding.
- Both the **perimetrium** and **myometrium** do not undergo these cyclical changes.

**Hint**: Think about which layer is affected by hormonal changes during the menstrual cycle.

### Step 4: Conclusion
The layer of the uterus wall that does not undergo cyclical changes is the **perimetrium** and **myometrium**. However, since the question asks for a specific layer, we can conclude that both the perimetrium and myometrium are correct answers, but typically, the perimetrium is often highlighted as the layer that remains unchanged.

**Final Answer**: The layer in the wall of the uterus that does not undergo cyclical changes is the **perimetrium**.