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Which of the following regents react (s)...

Which of the following regents react (s) with `C_6H_5CH_2CONH_2` to form `C_6H_5CH_2CN` ?

A

`P_2O_5`

B

`SOCl_2`

C

`POCl_3 " or " PCl_5`

D

All of the above

Text Solution

AI Generated Solution

The correct Answer is:
To solve the question of which reagents react with `C6H5CH2CONH2` (benzylamide) to form `C6H5CH2CN` (benzyl cyanide), we can analyze the potential reagents one by one. ### Step-by-Step Solution: 1. **Identify the Reaction Type**: The reaction we are looking at is the conversion of an amide (`C6H5CH2CONH2`) to a nitrile (`C6H5CH2CN`). This typically involves the removal of water (dehydration) and the introduction of a cyano group. 2. **Evaluate the Reagents**: We have four reagents to consider: - **P2O5**: This is a dehydrating agent known to remove water from amides, facilitating their conversion to nitriles. - **SOCl2 (Thionyl Chloride)**: This reagent is also a dehydrating agent and can convert amides to nitriles by replacing the amide group with a cyano group. - **POCl3 (Phosphoryl Chloride)** or **PCl5 (Phosphorus Pentachloride)**: Both of these reagents can act as chlorinating and dehydrating agents, which can also lead to the conversion of amides to nitriles. 3. **Reaction Mechanism**: - When `C6H5CH2CONH2` reacts with any of the above reagents, the mechanism generally involves the formation of an intermediate that loses a molecule of water, resulting in the formation of the nitrile `C6H5CH2CN`. 4. **Conclusion**: Since all three reagents (P2O5, SOCl2, and POCl3/PCl5) can facilitate the conversion of the amide to the nitrile through dehydration, the correct answer is that all of these reagents can react with `C6H5CH2CONH2` to form `C6H5CH2CN`. ### Final Answer: **All of the above (Option 4)** are correct reagents that can convert `C6H5CH2CONH2` to `C6H5CH2CN`.
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