The two most dreadful and fatal disease throughout world are :

Options

A. AIDS and malaria
B. Cancer and AIDS
C. Dengue and Tuberculosis
D. Polio and Leprosy

Answer

To solve the question regarding the two most dreadful and fatal diseases throughout the world, we will analyze the options provided and determine which diseases are considered incurable or have no effective treatment.

### Step-by-Step Solution:

1. **Understanding the Question**:
- We need to identify two diseases that are considered the most dreadful and fatal globally. The focus is on diseases that currently have no cure.

2. **Analyzing the Options**:
- **Option 1: AIDS and Malaria**:
- AIDS (Acquired Immunodeficiency Syndrome) has no cure, but malaria does have effective treatments available. Therefore, this option cannot be correct.

- **Option 2: Cancer and AIDS**:
- Cancer is a complex disease with various types, and while treatments like chemotherapy exist, they do not guarantee a cure and can only slow the progression. AIDS, on the other hand, has no definitive cure. This option seems plausible as both diseases are severe and lack a complete cure.

- **Option 3: Dengue and Tuberculosis**:
- Both dengue fever and tuberculosis have effective treatments available. Hence, this option is not correct.

- **Option 4: Polio and Leprosy**:
- Polio has a vaccine that prevents the disease, and leprosy also has effective treatment options. Thus, this option cannot be correct.

3. **Conclusion**:
- After analyzing all the options, the diseases that are most dreadful and fatal due to the lack of a complete cure are **Cancer and AIDS**. Therefore, the correct answer is **Option 2**.

### Final Answer:
The two most dreadful and fatal diseases throughout the world are **Cancer and AIDS**.