Select the odd out with respect to increased and decreased secretion of hormones .

Options

A. Diabetes mellitus
B. Grave's disease
C. Cretinism
D. Addison's disease

Answer

To solve the question of selecting the odd one out with respect to increased and decreased secretion of hormones, we can analyze each option provided:

1. **Diabetes Mellitus**: This condition is characterized by decreased levels of insulin, a hormone produced by the pancreas. Insulin is crucial for regulating blood glucose levels. Therefore, this option indicates decreased hormone secretion.

2. **Graves Disease**: This disorder is associated with increased levels of thyroxine (T4), a hormone produced by the thyroid gland. In Graves disease, the thyroid is overactive, leading to an excess of this hormone. Thus, this option indicates increased hormone secretion.

3. **Cretinism**: This condition results from decreased levels of thyroxine (T4) during development, leading to stunted growth and other developmental issues. Therefore, this option indicates decreased hormone secretion.

4. **Addison's Disease**: This disorder is characterized by decreased levels of hormones produced by the adrenal cortex, particularly cortisol and sometimes adrenaline. Hence, this option also indicates decreased hormone secretion.

Now, summarizing the findings:
- Diabetes Mellitus: Decreased insulin
- Graves Disease: Increased thyroxine
- Cretinism: Decreased thyroxine
- Addison's Disease: Decreased cortisol and adrenaline

From the analysis, we can see that the first, third, and fourth options involve decreased hormone secretion, while the second option (Graves Disease) involves increased hormone secretion. Therefore, the odd one out is:

**Answer: Graves Disease (Option 2)**