Which is not correctly matched ?

Options

A. Lipase - Hydrolysis of fats
B. Isomerases - Joining of similar substrate and management of substrate
C. Polymerase- chain elongation
D. DNA ligase - joins the DNA strand together by catalyzing the formation of phosphoester bonds.

Answer

To solve the question "Which is not correctly matched?", we need to analyze each enzyme and its corresponding function.

### Step-by-Step Solution:

1. **Lipase - Hydrolysis of Fat**:
- Lipase is an enzyme that catalyzes the hydrolysis of fats (lipids) into glycerol and fatty acids. This is a well-established function of lipase.
- **Conclusion**: This match is correct.

2. **Isomerases - Joining of Similar Substrate**:
- Isomerases are enzymes that catalyze the conversion of a molecule into one of its isomers. They do not join substrates; rather, they rearrange the structure of the same molecule.
- **Conclusion**: This match is incorrect.

3. **Polymerase - Chain Elongation**:
- Polymerases are enzymes that synthesize long chains or polymers by adding nucleotides to a growing DNA or RNA strand. This is a fundamental function of DNA polymerase and RNA polymerase.
- **Conclusion**: This match is correct.

4. **DNA Ligase - Joins DNA Strands**:
- DNA ligase is an enzyme that facilitates the joining of DNA strands together by catalyzing the formation of phosphodiester bonds. This is essential for DNA replication and repair.
- **Conclusion**: This match is correct.

### Final Answer:
The option that is not correctly matched is **Isomerases - Joining of Similar Substrate**.